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Towards spheroid-omics

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The MISpheroID knowledgebase records and organizes experimental parameters from thousands of cancer spheroid experiments, revealing heterogeneity and a lack of transparency in key spheroid research reporting practices.

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Fig. 1: Recommended minimum information for spheroid culture.

References

  1. Vinci, M. et al. BMC Biol. 10, 29 (2012).

    Article  CAS  Google Scholar 

  2. Kamatar, A., Gunay, G. & Acar, H. Polymers 12, (2020).

  3. Peirsman, A. et al. Nat. Methods https://doi.org/10.1038/s41592-021-01291-4 (2021).

  4. Taylor, C. F. et al. Nat. Biotechnol. 26, 889–896 (2008).

    Article  CAS  Google Scholar 

  5. Zanoni, M. et al. Sci. Rep. 6, 19103 (2016).

    Article  CAS  Google Scholar 

  6. Vande Voorde, J. et al. Sci. Adv. 5, eaau7314 (2019).

    Article  Google Scholar 

  7. Vadivelu, R. K. et al. Micromachines 8, 94 (2017).

    Article  Google Scholar 

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Acknowledgements

This work was supported by grants from the National Institutes of Health (NIH) National Cancer Institute (NCI) (New Innovator Award DP2CA250382-01), the National Science Foundation (NSF) (DMS1763272) and the Simons Foundation (594598 QN).

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Authors and Affiliations

  1. Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA

    Timothy L. Downing

  2. Department of Microbiology and Molecular Genetics, University of California Irvine, Irvine, CA, USA

    Timothy L. Downing

  3. UCI Edwards Lifesciences Foundation Cardiovascular Innovation and Research Center (CIRC), University of California Irvine, Irvine, CA, USA

    Timothy L. Downing

  4. NSF-Simons Center for Multiscale Cell Fate Research, University of California Irvine, Irvine, CA, USA

    Timothy L. Downing

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  1. Timothy L. Downing
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Correspondence to Timothy L. Downing.

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Downing, T.L. Towards spheroid-omics. Nat Methods 18, 1283–1285 (2021). https://doi.org/10.1038/s41592-021-01311-3

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