Skip to main content
Log in

Molecular visualization of cellular complexity

  • Comment
  • Published:

From Nature Methods

View current issue Submit your manuscript

Cryo-ET, which yields both structural and spatial information, will help unlock the molecular architecture of cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1: Cell architecture within a budding yeast cell, visualized by cryo-ET.

References

  1. Kendrew, J. C. et al. Nature 181, 662–666 (1958).

    Article  CAS  Google Scholar 

  2. Guo, Q. et al. Cell 172, 696–705.e12 (2018).

    Article  CAS  Google Scholar 

  3. Ader, N.R. et al. Elife 8, e40712 (2019).

    Article  Google Scholar 

  4. Zila, V. et al. Cell 184, 1032–1046.e18 (2021).

    Article  CAS  Google Scholar 

  5. O’Reilly, F. J. et al. Science 369, 554–557 (2020).

    Article  Google Scholar 

  6. von Kügelgen, A. et al. Cell 180, 348–358.e15 (2020).

    Article  Google Scholar 

  7. Schaffer, M. et al. Nat. Methods 16, 757–762 (2019).

    Article  CAS  Google Scholar 

  8. Weiss, G.L. et al. Science 369, 1005–1010 (2020).

    Article  CAS  Google Scholar 

  9. Pettersen, E. F. et al. Protein Sci. 30, 70–82 (2021).

    Article  CAS  Google Scholar 

  10. Kremer, J. R., Mastronarde, D. N. & McIntosh, J. R. J. Struct. Biol. 116, 71–76 (1996).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Wanda Kukulski.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wozny, M.R., Kukulski, W. Molecular visualization of cellular complexity. Nat Methods 18, 442–443 (2021). https://doi.org/10.1038/s41592-021-01131-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41592-021-01131-5

  • Springer Nature America, Inc.

Navigation