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Guiding human development in a dish

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Understanding of fundamental questions in human embryology is hampered by limited access to in utero developmental events. Manfrin et al. have engineered an in vitro platform that recapitulates early morphogenic events of human development with unprecedented spatial and temporal control.

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Fig. 1: Microfluidic device to control spatiotemporal diffusion of morphogen gradients.

Marina Corral Spence/Springer Nature

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Authors and Affiliations

  1. Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC, Los Angeles, CA, USA

    Leonardo Morsut & Giorgia Quadrato

  2. Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA

    Leonardo Morsut

Authors
  1. Leonardo Morsut
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  2. Giorgia Quadrato
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Correspondence to Leonardo Morsut or Giorgia Quadrato.

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Morsut, L., Quadrato, G. Guiding human development in a dish. Nat Methods 16, 585–586 (2019). https://doi.org/10.1038/s41592-019-0464-1

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  • DOI: https://doi.org/10.1038/s41592-019-0464-1

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