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Circuit interrogation in freely moving animals

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Developments in imaging tools are making it possible to record activity from both large neuronal populations and subcellular components in freely moving animals. Although these developments are enabling relationships between brain activity and complex behaviors to be explored, many challenges need to be overcome before the potential of the freely moving animal can be fully utilized.

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Fig. 1: Imaging data from miniature, head-mountable fluorescence microscopes.

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Authors and Affiliations

  1. Department of Behavior and Brain Organization, Research Center Caesar, Bonn, Germany

    Damian J. Wallace & Jason N. D. Kerr

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  1. Damian J. Wallace
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  2. Jason N. D. Kerr
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Correspondence to Damian J. Wallace or Jason N. D. Kerr.

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The authors declare no competing interests.

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Wallace, D.J., Kerr, J.N.D. Circuit interrogation in freely moving animals. Nat Methods 16, 9–11 (2019). https://doi.org/10.1038/s41592-018-0275-9

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