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Neurodegenerative diseases

Evidence for iatrogenic transmission of Alzheimer’s disease

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Credible evidence suggests that, under extraordinary circumstances, Alzheimer’s disease may be transmitted by a prion-like mechanism — yielding insights into both the basic biology of this neurodegenerative disorder and strategies for early prevention.

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Fig. 1: Iatrogenic Alzheimer’s disease.

References

  1. Prusiner, S. B. N. Engl. J. Med. 310, 661–663 (1984).

    Article  CAS  PubMed  Google Scholar 

  2. Brown, P. et al. Emerg. Infect. Dis. 18, 901–907 (2012).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Banerjee, G. et al. Nat. Med. https://doi.org/10.1038/s41591-023-02729-2 (2024).

  4. Prusiner, S. B. Annu. Rev. Genet. 47, 601–623 (2013).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Jucker, M. & Walker, L. C. Nature 501, 45–51 (2013).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  6. Long, J. M. & Holtzman, D. M. Cell 179, 312–339 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Banerjee, G. et al. J. Neurol. Neurosurg. Psychiat. 93, 693–700 (2022).

    Article  Google Scholar 

  8. Jaunmuktane, Z. et al. Acta Neuropathol. 142, 211–215 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Boyd, A. et al. Med. J. Aust. 193, 366–369 (2010).

    Article  PubMed  Google Scholar 

  10. Purro, S. A. et al. Nature 564, 415–419 (2018).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  11. Eisele, Y. S. et al. Science 330, 980–982 (2010).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  12. Lauwers, E. et al. Lancet Neurol. 19, 872–878 (2020).

    Article  CAS  PubMed  Google Scholar 

  13. Jucker, M. & Walker, L. C. Nature 525, 193–194 (2015).

    Article  ADS  CAS  PubMed  Google Scholar 

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Correspondence to Mathias Jucker or Lary C. Walker.

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Jucker, M., Walker, L.C. Evidence for iatrogenic transmission of Alzheimer’s disease. Nat Med 30, 344–345 (2024). https://doi.org/10.1038/s41591-023-02768-9

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