Skip to main content

Advertisement

Log in

Autoimmune disease is the next frontier for CAR T cell therapy

  • News Feature
  • Published:

From Nature Medicine

View current issue Submit your manuscript

CAR T cell therapy has transformed the treatment of B cell cancers and is now being pursued by biotech companies for conditions as varied as systemic lupus erythematosus, diabetes and organ rejection.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1: Targeted killing by a CAR T cell.

References

  1. Kansal, R. et al. Sci. Transl. Med. 11, eaav1648 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Mougiakakos, D. et al. New Engl. J. Med. 385, 567–569 (2021).

    Article  PubMed  Google Scholar 

  3. Mackensen, A. et al. Nat. Med. 28, 2124–2132 (2022).

    Article  CAS  PubMed  Google Scholar 

  4. Klatzmann, D. et al. Science 225, 59–63 (1984).

    Article  CAS  PubMed  Google Scholar 

  5. Harrison, A. J., Du, X., von Scheidt, B., Kershaw, M. H. & Slaney, C. L. Immunother. Adv. 1, ltab016 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Arnold, C. Autoimmune disease is the next frontier for CAR T cell therapy. Nat Med 30, 6–9 (2024). https://doi.org/10.1038/s41591-023-02716-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41591-023-02716-7

  • Springer Nature America, Inc.

This article is cited by

Navigation