We characterized cancer cells, immune responses and the microbiota composition in a cohort of primary colon cancers. Multi-omic analyses defined parameters associated with favorable prognosis, including a score that captured the intratumoral immune response and a specific microbiome signature. This data repository (atlas and compass of immune–cancer–microbiome interactions (AC-ICAM)) is publicly available.
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This is a summary of: Roelands, J. et al. An integrated tumor, immune and microbiome atlas of colon cancer. Nat. Med. https://doi.org/10.1038/s41591-023-02324-5 (2023).
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Immune–microbiota interactions affect the prognosis of patients with colon cancer. Nat Med 29, 1076–1077 (2023). https://doi.org/10.1038/s41591-023-02384-7
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DOI: https://doi.org/10.1038/s41591-023-02384-7
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