References
Locke, F. L. et al. New Engl. J. Med. 386, 640–654 (2022).
Kamdar, M. et al. Lancet 399, 2294–2308 (2022).
Jacobson, C. A. et al. J. Clin. Oncol. 38, 3095–3106 (2020).
Bethge, W. A. et al. Blood 140, 349–358 (2022).
Jain, M. D. et al. Blood 137, 2621–2633 (2021).
Shadman, M. et al. Blood 139, 1330–1339 (2022).
Armand, P. et al. Br. J. Haematol. 160, 608–617 (2013).
Kurtz, D. M. et al. J. Clin. Oncol. 36, 2845–2853 (2018).
Wang, Y. et al. J Clin. Oncol. 37, 1819–1827 (2019).
Lin, J. K. et al. J. Clin. Oncol. 37, 2105–2119 (2019).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
R.W.M has served as a consultant for Genmab/AbbVie, Adaptive Biotechnologies, Bristol-Myers Squibb, Intellia and Epizyme and received research funding (institutional) from Merck, Bristol-Myers Squibb, Genentech/Roche and Genmab. P.A. has served as a consultant for Merck, Bristol-Myers Squibb, Pfizer, Affimed, Adaptive, Infinity, ADC Therapeutics, Celgene and MorphoSys; received research funding (institutional) from Merck, Bristol-Myers Squibb, Affimed, Adaptive, Roche, Tensha, Otsuka, Sigma-Tau, Genentech and IGM; and received honoraria from Bristol-Myers Squibb and Merck. C.A.J. has served as a consultant for Kite, Novartis, Pfizer, Humanigen, Precision Bioscience, Bayer and Celgene and has received research funding from Pfizer and Kite.
Rights and permissions
About this article
Cite this article
Cliff, E.R.S., Merryman, R.W., Armand, P. et al. Unresolved questions in the second-line use of CAR-T cells for diffuse large B cell lymphoma. Nat Med 28, 2458–2459 (2022). https://doi.org/10.1038/s41591-022-02067-9
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41591-022-02067-9
- Springer Nature America, Inc.