A trimodal single-cell assay reveals a previously unknown T cell subset and cellular state differences between children and older adults that might contribute to age-specific immunity.
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References
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This is a summary of: Thomson, Z. et al. Trimodal single cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment. Nat. Immunol. https://doi.org/10.1038/s41590-023-01641-8 (2023).
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Unraveling age-specific complexity in the human T cell compartment. Nat Immunol 24, 1799–1800 (2023). https://doi.org/10.1038/s41590-023-01653-4
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DOI: https://doi.org/10.1038/s41590-023-01653-4
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