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Stromal immunology

New fibroblast network connections support lymphocytic cellular service

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Single-cell RNA sequencing distinguishes subsets of fibroblastic reticular cells and predicts pathways that support immune function via crosstalk with lymphocytes.

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Fig. 1: Heterogeneity of fibroblastic reticular cells in secondary lymphoid organs in humans and mice.

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia

    Anne L. Fletcher & Kim L. Good-Jacobson

  2. Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia

    Anne L. Fletcher & Kim L. Good-Jacobson

Authors
  1. Anne L. Fletcher
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  2. Kim L. Good-Jacobson
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Corresponding authors

Correspondence to Anne L. Fletcher or Kim L. Good-Jacobson.

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Competing interests

A.F. is a consultant and member of the scientific advisory board of Phenomic AI. K.L.G.-J. declares no competing interests.

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Fletcher, A.L., Good-Jacobson, K.L. New fibroblast network connections support lymphocytic cellular service. Nat Immunol 24, 1054–1055 (2023). https://doi.org/10.1038/s41590-023-01537-7

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