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T CELL MEMORY

An old BATF’s new T-ricks

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Two studies reveal a role for the transcriptional regulator BATF3 as a T cell–intrinsic factor mediating effective memory responses. This finding opens future avenues of investigation and opportunities to enhance cellular immunotherapy.

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Fig. 1: Pleiotropic functions of BATF3 in cDCs and T cells.

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Acknowledgements

C.A.L. is supported by a Stanford Science Fellowship. A.T.S. is supported by a Parker Bridge Scholar Award from the Parker Institute for Cancer Immunotherapy and a Career Award for Medical Scientists from the Burroughs Wellcome Fund.

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Authors and Affiliations

  1. Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA

    Caleb A. Lareau & Ansuman T. Satpathy

  2. Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA

    Ansuman T. Satpathy

Authors
  1. Caleb A. Lareau
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  2. Ansuman T. Satpathy
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Corresponding author

Correspondence to Ansuman T. Satpathy.

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Competing interests

A.T.S. is a scientific founder of Immunai and receives research funding from Arsenal Biosciences.

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Lareau, C.A., Satpathy, A.T. An old BATF’s new T-ricks. Nat Immunol 21, 1309–1310 (2020). https://doi.org/10.1038/s41590-020-0796-0

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