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TISSUE RESIDENT T CELLS

Resident memory T cells show that it is never too late to change your ways

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Immunological memory is a crucial feature of adaptive immunity. A new report proposes a novel ‘outside-in’ mechanism by which a recall immune response may be initiated from the tissue, rather than secondary lymphoid organs.

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Fig. 1: Models of memory T cell migration.

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Authors and Affiliations

  1. Department of Biosciences, University of Salzburg, Salzburg, Austria

    Iris K. Gratz

  2. Benaroya Research Institute, Seattle, WA, USA

    Iris K. Gratz & Daniel J. Campbell

  3. EB House Austria, Department of Dermatology, University Hospital of the Paracelsus Medical University, Salzburg, Austria

    Iris K. Gratz

  4. Department of Immunology, University of Washington School of Medicine, Seattle, WA, USA

    Daniel J. Campbell

Authors
  1. Iris K. Gratz
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  2. Daniel J. Campbell
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Correspondence to Iris K. Gratz or Daniel J. Campbell.

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The authors declare no competing interests.

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Gratz, I.K., Campbell, D.J. Resident memory T cells show that it is never too late to change your ways. Nat Immunol 21, 359–360 (2020). https://doi.org/10.1038/s41590-020-0637-1

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