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INTERFERON-λ

The IFN-λ Pony Express

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The mechanisms by which the cytokine IFN-λ regulates adaptive immune responses are poorly understood. A new study now reveals a novel IFN-λ-mediated signal-transmission system that enhances immunity after infection of the mouse respiratory tract with influenza virus.

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Fig. 1: Regulation of immune cells by IFN-λ.

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Authors and Affiliations

  1. Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland

    Stefan F. Wieland & Markus H. Heim

  2. Division of Gastroenterology and Hepatology, University Hospital Basel, Basel, Switzerland

    Markus H. Heim

Authors
  1. Stefan F. Wieland
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  2. Markus H. Heim
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Correspondence to Stefan F. Wieland.

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The authors declare no competing interests.

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Wieland, S.F., Heim, M.H. The IFN-λ Pony Express. Nat Immunol 20, 522–524 (2019). https://doi.org/10.1038/s41590-019-0362-9

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