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Mucosal immunology

Decoding the intestinal epithelium cell by cell

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Single-cell sequencing identifies novel subtypes of intestinal epithelial cells and their molecular signatures, which reveals new principles for gut homeostasis and the response to infection.

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Fig. 1: Novel IEC subtypes and gene signatures under homeostasis and in response to bacterial and helminth infection.

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Authors and Affiliations

  1. Nomis Center for Immunology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, CA, USA

    Yujung Michelle Lee & Janelle S. Ayres

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  1. Yujung Michelle Lee
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  2. Janelle S. Ayres
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Correspondence to Janelle S. Ayres.

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The authors declare no competing financial interests.

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Lee, Y.M., Ayres, J.S. Decoding the intestinal epithelium cell by cell. Nat Immunol 19, 7–9 (2018). https://doi.org/10.1038/s41590-017-0011-0

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