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Glycobiology

Visualizing the structural diversity of glycoconjugates

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Analyzing glycans is challenging because of their structural diversity and complexity and the lack of analytical techniques capable of resolving pools of similar glycan structures. A new method now enables imaging of single glycans, providing direct observation of individual glycans and glycoconjugates.

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Fig. 1: STM imaging of human MUC1 decorated with O-glycans.

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Correspondence to Martina Delbianco or Yu Ogawa.

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Delbianco, M., Ogawa, Y. Visualizing the structural diversity of glycoconjugates. Nat Chem Biol 20, 11–12 (2024). https://doi.org/10.1038/s41589-023-01502-3

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