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Lipids and signaling

Do lipids tune B cell signaling?

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The role of lipid membrane domains in the activation of immune cells remains elusive. New microscopy data on B cell signaling support a mechanism in which lipid membrane domains consolidate upon B cell receptor clustering.

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Fig. 1: B cell signaling is tuned by lipid membrane heterogeneity.

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Authors and Affiliations

  1. Jožef Stefan Institute, Ljubljana, Slovenia

    Iztok Urbančič

  2. Institute of Applied Optics and Biophysics, Friedrich Schiller University Jena, Jena, Germany

    Christian Eggeling

  3. Leibniz Institute of Photonic Technology, Jena, Germany

    Christian Eggeling

  4. Jena Center for Soft Matter, Jena, Germany

    Christian Eggeling

  5. Science for Life Laboratory, Department of Women’s and Children’s Health, Karolinska Institutet, Solna, Sweden

    Erdinc Sezgin

Authors
  1. Iztok Urbančič
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  2. Christian Eggeling
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  3. Erdinc Sezgin
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Corresponding author

Correspondence to Christian Eggeling.

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The authors declare no competing interests.

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Urbančič, I., Eggeling, C. & Sezgin, E. Do lipids tune B cell signaling?. Nat Chem Biol 19, 669–670 (2023). https://doi.org/10.1038/s41589-023-01303-8

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  • DOI: https://doi.org/10.1038/s41589-023-01303-8

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