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Mining microbial metabolism

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Comamonas testosteroni utilizes aromatic compounds such as monomers from lignin and plastics, but the underlying metabolic pathways were elusive. Multi-omics analysis now clarifies the multifaceted regulation of its metabolism, facilitating strain engineering to convert substrates from lignin and plastics into valuable bioproducts.

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Fig. 1: Understanding the valorization of products derived from lignin and plastics by C. testosteroni.

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Authors and Affiliations

  1. Washington University in St. Louis, St. Louis, MO, USA

    Yinjie J. Tang & Tae Seok Moon

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  1. Yinjie J. Tang
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  2. Tae Seok Moon
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Correspondence to Yinjie J. Tang or Tae Seok Moon.

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The authors declare no competing interests.

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Tang, Y.J., Moon, T.S. Mining microbial metabolism. Nat Chem Biol 19, 544–545 (2023). https://doi.org/10.1038/s41589-023-01257-x

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