Cas12f1 is a member of type V Cas12 family, which has a hypercompact size. A Cas12f1-based adenine base editor has now been developed that is small enough to be loaded into a single AAV vector without compromising editing activity.
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16 February 2023
A Correction to this paper has been published: https://doi.org/10.1038/s41589-023-01266-w
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Song, B., Bae, S. Voyage to minimal base editors. Nat Chem Biol 18, 920–921 (2022). https://doi.org/10.1038/s41589-022-01101-8
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DOI: https://doi.org/10.1038/s41589-022-01101-8
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