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Toward spatially resolved metabolomics

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Coherent Raman imaging enables mapping of chemical features at subcellular resolution, setting the stage for tracking lipids and other metabolites in intact living systems.

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Fig. 1: Imaging of anaesthetized worms via BCARS reveals chemically distinct classes of lipid droplets in the intestine and epidermis and enables the tracking of lipid turnover.

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  1. Boyce Thompson Institute and Cornell University, Ithaca, NY, USA

    Bennett W. Fox & Frank C. Schroeder

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  1. Bennett W. Fox
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  2. Frank C. Schroeder
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Correspondence to Frank C. Schroeder.

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The authors declare no competing interests.

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Fox, B.W., Schroeder, F.C. Toward spatially resolved metabolomics. Nat Chem Biol 16, 1039–1040 (2020). https://doi.org/10.1038/s41589-020-00650-0

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