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SYNTHETIC BIOLOGY

Polar-opposite fates

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Asymmetric cell division, which generates daughter cells with distinct characteristics, is a mechanism for creating complex systems through cellular differentiation. Two studies in this issue develop synthetic platforms that program spatial localization of genetic material or signaling molecules to enable asymmetric cell division in Escherichia coli.

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Fig. 1: Cellular differentiation through asymmetric cell division.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Duke University, Durham, NC, USA

    Helena R. Ma & Lingchong You

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  1. Helena R. Ma
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  2. Lingchong You
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Correspondence to Lingchong You.

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The authors declare no competing interests.

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Ma, H.R., You, L. Polar-opposite fates. Nat Chem Biol 15, 850–852 (2019). https://doi.org/10.1038/s41589-019-0337-z

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