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Metabolic diseases

New insights into the genetics of diabetes in pregnancy

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Gestational diabetes is a complex metabolic condition thought to have a strong genetic predisposition. A large genome-wide association study of participants from Finland sheds light on the genetic contributors, opening avenues for research into mechanisms that underlie glucose regulation in pregnancy to improve the health of mothers and babies.

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Fig. 1: Prior associations of 14 genome-wide significant loci for GDM with T2D and fasting glucose levels.

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Authors and Affiliations

  1. Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK

    Aminata Hallimat Cissé & Rachel M. Freathy

Authors
  1. Aminata Hallimat Cissé
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  2. Rachel M. Freathy
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Correspondence to Rachel M. Freathy.

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The authors declare no competing interests.

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Cissé, A.H., Freathy, R.M. New insights into the genetics of diabetes in pregnancy. Nat Genet 56, 358–359 (2024). https://doi.org/10.1038/s41588-024-01675-0

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