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Connecting clinical and genetic heterogeneity in ADHD

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Understanding clinical heterogeneity in attention deficit hyperactivity disorder (ADHD) is important for improving personalized care and long-term outcomes. A study exploits the large scale and breadth of phenotyping of the iPSYCH cohort to link clinical heterogeneity to genetic heterogeneity in ADHD.

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Fig. 1: Relationships between ADHD-adjacent traits and polygenic scores.

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Acknowledgements

J.G. is supported by the Australian National Health and Medical Research Council (GNT2018431) and Mater Foundation.

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Authors and Affiliations

  1. Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia

    Chloe X. Yap & Jacob Gratten

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  1. Chloe X. Yap
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  2. Jacob Gratten
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Correspondence to Chloe X. Yap.

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The authors declare no competing interests.

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Yap, C.X., Gratten, J. Connecting clinical and genetic heterogeneity in ADHD. Nat Genet 56, 195–196 (2024). https://doi.org/10.1038/s41588-024-01652-7

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