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DISEASE GENETICS

Finding causal genes underlying risk for coronary artery disease

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Previous genome-wide association studies of coronary artery disease (CAD) have discovered multiple susceptibility loci but have largely failed to uncover causal genes. A new study identifies hundreds of likely causal genes underlying the genetic risk for CAD.

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Fig. 1: Filtering GWAS loci into causal genes and variants.

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Correspondence to Paul L. Auer.

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Auer, P.L. Finding causal genes underlying risk for coronary artery disease. Nat Genet 54, 1768–1769 (2022). https://doi.org/10.1038/s41588-022-01094-z

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