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NEUROGENOMICS

Scrutinizing disease states and regulation in human microglia

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Single-cell and bulk transcriptomics of adult human microglia from a population of individuals reveals activated states across several brain disorders and maps Alzheimer’s disease variants to microglia-enriched genes.

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Fig. 1: Molecular mapping of human microglia.

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Authors and Affiliations

  1. Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA

    Kevin W. Kelley & Sergiu P. Pașca

  2. Stanford Brain Organogenesis, Wu Tsai Neuroscience Institute, Stanford University, Stanford, CA, USA

    Kevin W. Kelley & Sergiu P. Pașca

Authors
  1. Kevin W. Kelley
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  2. Sergiu P. Pașca
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Correspondence to Sergiu P. Pașca.

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The authors declare no competing interests.

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Kelley, K.W., Pașca, S.P. Scrutinizing disease states and regulation in human microglia. Nat Genet 53, 766–767 (2021). https://doi.org/10.1038/s41588-021-00826-x

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  • DOI: https://doi.org/10.1038/s41588-021-00826-x

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