Efforts to systematically characterize silencers in animal genomes have been limited. Two studies in this issue of Nature Genetics bring silencers into the spotlight, identifying these elements genome wide in human and mouse cells, and providing insights into their function.
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Della Rosa, M., Spivakov, M. Silencers in the spotlight. Nat Genet 52, 244–245 (2020). https://doi.org/10.1038/s41588-020-0583-8
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DOI: https://doi.org/10.1038/s41588-020-0583-8
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