We developed the OMArk software package for evaluating protein-coding gene annotation quality. In addition to assessing the completeness of a proteome, OMArk estimates the overall quality of the gene set’s content, a feature that will help to improve public protein sequence data.
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References
Blaxter, M. et al. Why sequence all eukaryotes? Proc. Natl Acad. Sci. USA 119, e2115636118 (2022). An article that presents the reasoning behind the ongoing massive sequencing of all eukaryotic genomes.
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This is a summary of: Nevers, Y. et al. Quality assessment of gene repertoire annotations with OMArk. Nat. Biotechnol. https://doi.org/10.1038/s41587-024-02147-w (2024).
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OMArk, a tool for gene annotation quality control, reveals erroneous gene inference. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02155-w
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DOI: https://doi.org/10.1038/s41587-024-02155-w
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