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A mucin degrader for cancer therapy

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A new approach to targeting mucins via protein degradation shows promise against cancer.

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Fig. 1: Action of the HER2-targeted mucinase anti-HER2–eStcE and the resultant change in immunological landscape.

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Authors and Affiliations

  1. Centre for Inflammation and Tissue Repair, University College London, London, UK

    Richard Beatson

  2. School of Cancer and Pharmaceutical Sciences, King’s College London, London, UK

    Richard Beatson & Joy M. Burchell

Authors
  1. Richard Beatson
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  2. Joy M. Burchell
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Corresponding author

Correspondence to Joy M. Burchell.

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The authors declare no competing interests.

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Beatson, R., Burchell, J.M. A mucin degrader for cancer therapy. Nat Biotechnol 42, 572–573 (2024). https://doi.org/10.1038/s41587-023-01984-5

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