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MaxFuse enables data integration across weakly linked spatial and single-cell modalities

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Data integration between weakly linked single-cell modalities is challenging using existing methods. Therefore, we developed MaxFuse to enable matching and integration between cells from modalities such as single-cell spatial proteomic datasets and single-cell transcriptomic datasets, or other modalities where features are only weakly correlated.

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Fig. 1: The MaxFuse pipeline and an example application in human tissue.

References

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This is a summary of: Chen, S. et al. Integration of spatial and single-cell data across modalities with weakly linked features. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-01935-0 (2023).

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MaxFuse enables data integration across weakly linked spatial and single-cell modalities. Nat Biotechnol (2023). https://doi.org/10.1038/s41587-023-01943-0

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  • DOI: https://doi.org/10.1038/s41587-023-01943-0

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