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Deciphering the human phosphoproteome

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Machine learning provides a functional score for ~120,000 human phosphorylation sites.

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Fig. 1: Reanalysis of phosphoproteomics datasets in the PRIDE database provides functional scores for individual phosphosites.

References

  1. Olsen, J. V. et al. Cell 127, 635–648 (2006).

    Article  CAS  Google Scholar 

  2. Needham, E.J., Parker, B.L., Burykin, T., James, D.E. & Humphrey, S.J. Sci. Signal. 12, eaau8645 (2019).

    Article  CAS  Google Scholar 

  3. Ochoa, D. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-019-0344-3 (2019).

  4. Wilson, L. J. et al. Cancer Res. 78, 15–29 (2018).

    Article  CAS  Google Scholar 

  5. Hornbeck, P. V. et al. Nucleic Acids Res. 43, D512–D520 (2015).

    CAS  Google Scholar 

  6. Casado, P. et al. Sci. Signal. 6, rs6 (2013).

    Article  Google Scholar 

  7. Beekhof, R. et al. Mol. Syst. Biol. 15, e8981 (2019).

    Article  Google Scholar 

  8. Francavilla, C. et al. Nat. Struct. Mol. Biol. 23, 608–618 (2016).

    Article  CAS  Google Scholar 

  9. Perez-Riverol, Y. et al. Nucleic Acids Res. 47D1, D442–D450 (2019).

    Article  Google Scholar 

  10. Lundby, A. et al. Cell 179, 543–560.e26 (2019).

    Article  CAS  Google Scholar 

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Correspondence to Jesper V. Olsen.

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Franciosa, G., Martinez-Val, A. & Olsen, J.V. Deciphering the human phosphoproteome. Nat Biotechnol 38, 285–286 (2020). https://doi.org/10.1038/s41587-020-0441-3

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