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Specter of eye toxicity looms over BCMA-targeted therapy

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The first antibody–drug conjugate to treat multiple myeloma can spur reversible loss of vision, but that may not be the case for other anti-BCMA T-cell therapies or bispecific antibodies.

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Dolgin, E. Specter of eye toxicity looms over BCMA-targeted therapy. Nat Biotechnol 38, 1363–1365 (2020). https://doi.org/10.1038/s41587-020-00757-8

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