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Integrating scientific considerations into R&D project valuation

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Traditional valuation approaches rarely take into account scientific considerations specific to a R&D project. A question-based approach using real options offers a solution.

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Fig. 1: Decision tree of the younamamab case based on the QBCD analysis using the QOC tool.

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Author information

Authors and Affiliations

  1. The Netherlands Organisation for Health Research and Development (ZonMw), The Hague, the Netherlands

    Saco J. de Visser

  2. Centre for Human Drug Research (CHDR InnoS), Leiden, the Netherlands

    Adam F. Cohen

  3. Paul Janssen Futurelab, Leiden University Medical Center, Leiden, the Netherlands

    Marcel J. H. Kenter

Authors
  1. Saco J. de Visser
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  2. Adam F. Cohen
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  3. Marcel J. H. Kenter
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Corresponding author

Correspondence to Saco J. de Visser.

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The authors declare no competing interests.

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Supplementary Materials

Supplementary Figs. 1 and 2 and Supplementary Table 1

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de Visser, S.J., Cohen, A.F. & Kenter, M.J.H. Integrating scientific considerations into R&D project valuation. Nat Biotechnol 38, 14–18 (2020). https://doi.org/10.1038/s41587-019-0358-x

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