Skip to main content
Log in

MICROBIOLOGY

Culturing the uncultured

  • News & Views
  • Published:

From Nature Biotechnology

View current issue Submit your manuscript

Bacterial species that have eluded cultivation are selectively brought into culture.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1: Overview of reverse genomics for the isolation and cultivation of bacteria.

References

  1. Hug, L. A. et al. Nat. Microbiol. 1, 16048 (2016).

    Article  CAS  PubMed  Google Scholar 

  2. Lloyd, K. G., Steen, A. D., Ladau, J., Yin, J. & Crosby, L. mSystems 3, e00055–18 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Rappé, M. S. & Giovannoni, S. J. Annu. Rev. Microbiol. 57, 369–394 (2003).

    Article  PubMed  Google Scholar 

  4. Steen, A.D. et al. ISME J. https://doi.org/10.1038/s41396-019-0484-y (2019).

  5. Cross, K. L. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-019-0260-6 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Brown, C. T. et al. Nature 523, 208–211 (2015).

    Article  CAS  PubMed  Google Scholar 

  7. He, X. et al. Proc. Natl. Acad. Sci. USA 112, 244–249 (2015).

    Article  CAS  PubMed  Google Scholar 

  8. Browne, H. P. et al. Nature 533, 543–546 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. McInerney, M. J., Sieber, J. R. & Gunsalus, R. P. Curr. Opin. Biotechnol. 20, 623–632 (2009).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Carini, P. A. mSystems 4, e00092–19 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Thijs J. G. Ettema.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lewis, W.H., Ettema, T.J.G. Culturing the uncultured. Nat Biotechnol 37, 1278–1279 (2019). https://doi.org/10.1038/s41587-019-0300-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41587-019-0300-2

  • Springer Nature America, Inc.

This article is cited by

Navigation