Centralization of care for penile cancer has been underscored in the 2023 updated EAU–ASCO guidelines. Expertise consolidation enhances patient care, addressing penile cancer complexities from diagnosis to treatment. Centralization initiatives, like the European Reference Networks, and dedicated scientific societies have crucial roles in guiding centralized care pathways to ultimately improve patient outcomes.
References
Brouwer, O. R. et al. European Association of Urology-American Society of Clinical Oncology Collaborative Guideline on Penile Cancer: 2023 update. Eur. Urol. 83, 548–560 (2023).
Bandini, M. et al. A global approach to improving penile cancer care. Nat. Rev. Urol. 19, 231–239 (2022).
Hegarty, P. K. & Zafirakis, H. Organ-sparing surgery in penile cancer: a call for centralization of surgery. Nat. Rev. Urol. 18, 191–192 (2021).
Canter, D. J. et al. The International Penile Advanced Cancer Trial (InPACT): rationale and current status. Eur. Urol. Focus 5, 706–709 (2019).
Crook, J., Black, P. C., Spiess, P. E. & Pettaway, C. The first International Penile Advanced Cancer Trial (InPACT) opens in Canada! Why additional centers are needed. Can. Urol. Assoc. J. 16, 70–71 (2022).
Cornes, R. & Earle, W. Current unmet needs in penile cancer: the way forward? Semin. Oncol. Nurs. 38, 151282 (2022).
De Vries, H. M. et al. Atezolizumab with or without radiotherapy for advanced squamous cell carcinoma of the penis (the PERICLES study): a phase II trial. J. Clin. Oncol. 41, 4872–4880 (2023).
Vanthoor, J., Thomas, A., Tsaur, I. & Albersen, M. Making surgery safer by centralization of care: impact of case load in penile cancer. World J. Urol. 38, 1385–1390 (2020).
Oomen, L. et al. Rare and complex urology: clinical overview of ERN eUROGEN. Eur. Urol. 81, 204–212 (2022).
Thiagarajan, S. et al. National cancer grid virtual tumor boards of head and neck cancers: an innovative approach to multidisciplinary care. JCO Glob. Oncol. 9, e2200348 (2023).
Acknowledgements
This work was carried out on behalf of the Global Society of Rare Genitourinary Tumors (GSRGT).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Additional information
Related links
Global Cancer Observatory: https://gco.iarc.who.int/en
Rights and permissions
About this article
Cite this article
Basile, G., Necchi, A., Prakash, G. et al. The case for centralization of care in penile cancer — respecting geographical needs. Nat Rev Urol (2024). https://doi.org/10.1038/s41585-024-00879-7
Published:
DOI: https://doi.org/10.1038/s41585-024-00879-7
- Springer Nature Limited