Drug-free remission is a treatment goal in rheumatoid arthritis that can be achieved by tapering and discontinuation of biologic DMARDs. However, newly published real-world evidence suggests that DMARD discontinuation occurs less frequently than results of clinical trials suggest, so it is important to question what the ultimate goal of treatment should be.
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Fautrel, B. Biologics in rheumatoid arthritis: a lifetime treatment or possibility of drug holidays?. Nat Rev Rheumatol 19, 611–612 (2023). https://doi.org/10.1038/s41584-023-01005-4
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DOI: https://doi.org/10.1038/s41584-023-01005-4
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