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The Musculoskeletal Knowledge Portal: improving access to multi-omics data

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From Nature Reviews Rheumatology

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Built by and for the research community, the Musculoskeletal Knowledge Portal (MSK-KP) offers researchers a single integrated platform on which to display, access, distill and explore results from large genomic and epigenomic studies to formulate hypotheses and accelerate the development of patient-centered therapeutics for complex, multi-factorial conditions such as osteoarthritis.

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Fig. 1: The Musculoskeletal Knowledge Portal serves the research community.

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Authors and Affiliations

  1. Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA

    Jennifer J. Westendorf

  2. Indiana Center for Musculoskeletal Health, Indiana University, Indianapolis, IN, USA

    Lynda F. Bonewald

  3. Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA

    Douglas P. Kiel

  4. Department of Medicine, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, USA

    Douglas P. Kiel

  5. Broad Institute of MIT & Harvard, Boston and Cambridge, Cambridge, MA, USA

    Douglas P. Kiel & Noël P. Burtt

Authors
  1. Jennifer J. Westendorf
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  2. Lynda F. Bonewald
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  3. Douglas P. Kiel
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  4. Noël P. Burtt
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Corresponding author

Correspondence to Jennifer J. Westendorf.

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Competing interests

D.P.K. declares he has received grant funding to his institution from Amgen, Radius Health and Solarea Bio; serves on scientific advisory boards for Pfizer and Solarea Bio; and has received royalties for publication in UpToDate from Wolters Kluwer. The other authors declare no competing interests.

Additional information

Related links

Bonebase: https://bonebase.lab.uconn.edu/

Genetics of Osteoarthritis Consortium: https://www.genetics-osteoarthritis.com/

Human Cell Atlas: https://www.humancellatlas.org/

International Federation of Musculoskeletal Research Societies: https://www.ifmrs.org/

Knowledge Portal Network: https://kp4cd.org/

Musculoskeletal Knowledge Portal: https://msk.hugeamp.org/

Single Cell Portal: https://singlecell.broadinstitute.org/single_cell

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Westendorf, J.J., Bonewald, L.F., Kiel, D.P. et al. The Musculoskeletal Knowledge Portal: improving access to multi-omics data. Nat Rev Rheumatol 18, 1–2 (2022). https://doi.org/10.1038/s41584-021-00711-1

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