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Neuromuscular disease

Advances in the therapeutic algorithm for myasthenia gravis

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New biologics are rapidly opening up target-specific therapeutic opportunities for myasthenia gravis (MG) — an autoimmune disease caused by antibodies against neuromuscular junction proteins. Two recent trials have now demonstrated the efficacy and tolerability of the complement C5 inhibitor zilucoplan and the FcRn inhibitor rozanolixizumab in patients with generalized MG.

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Authors and Affiliations

  1. Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA

    Marinos C. Dalakas

  2. Neuroimmunology Unit, National and Kapodistrian University, University of Athens Medical School, Athens, Greece

    Marinos C. Dalakas

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  1. Marinos C. Dalakas
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Correspondence to Marinos C. Dalakas.

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Dalakas, M.C. Advances in the therapeutic algorithm for myasthenia gravis. Nat Rev Neurol 19, 393–394 (2023). https://doi.org/10.1038/s41582-023-00825-y

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