A high-salt diet leads to the development of hallmark Alzheimer disease (AD) pathology and cognitive impairment in mice, according to new research published in Nature. The study reveals previously unknown molecular mechanisms that could have therapeutic implications.
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Faraco, G. et al. Dietary salt promotes cognitive impairment through tau phosphorylation. Nature 574, 686–690 (2019)
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Fyfe, I. High-salt diet promotes Alzheimer disease-like changes. Nat Rev Neurol 16, 2–3 (2020). https://doi.org/10.1038/s41582-019-0289-7
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DOI: https://doi.org/10.1038/s41582-019-0289-7
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