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Can imaging extend the thrombolytic time window after stroke?

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A new trial has demonstrated the benefits of intravenous thrombolysis, guided by perfusion imaging, 4.5–9.0 h after stroke onset and in individuals with wake-up stroke. In addition to extending the time window for thrombolysis after acute ischaemic stroke, these findings could aid the refinement of imaging and thrombolytic protocols.

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Fig. 1: Reperfusion therapy in the late time window.

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Acknowledgements

M.L. is supported by the National Natural Science Foundation of China (grant number 81622017), the National Key Research and Development Program of China (grant number 2016YFC1301503) and the Science Technology Department of Zhejiang Province (grant number 2018C04011).

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Correspondence to Min Lou.

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Lou, M. Can imaging extend the thrombolytic time window after stroke?. Nat Rev Neurol 15, 496–498 (2019). https://doi.org/10.1038/s41582-019-0232-y

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