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The many regulators of epithelial−mesenchymal transition

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Epithelial−mesenchymal transition (EMT) is a complex, highly regulated process that is reportedly controlled by hundreds of transcription factors and hundreds of microRNAs. Here we discuss whether the complexity of the process necessitates so many regulators, or whether many ‘false positives’ are reported in the literature.

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Authors and Affiliations

  1. Centre for Cancer Biology, an alliance of SA Pathology and the University of South Australia, Adelaide, Australia

    Cameron P. Bracken & Gregory J. Goodall

  2. Discipline of Medicine and the Faculty of Health Science, University of Adelaide, Adelaide, Australia

    Cameron P. Bracken & Gregory J. Goodall

Authors
  1. Cameron P. Bracken
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  2. Gregory J. Goodall
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The authors contributed equally to the writing and revision of the article.

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Correspondence to Cameron P. Bracken or Gregory J. Goodall.

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The authors declare no competing interests.

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Nature Reviews Molecular Cell Biology thanks the anonymous reviewers for their contribution to the peer review of this work.

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Bracken, C.P., Goodall, G.J. The many regulators of epithelial−mesenchymal transition. Nat Rev Mol Cell Biol 23, 89–90 (2022). https://doi.org/10.1038/s41580-021-00442-x

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