Wastewater genomic surveillance can transform global viral disease monitoring. This Genome Watch article explores the techniques, analytical pipelines and implications for public health.
References
Karthikeyan, S. et al. Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission. Nature 609, 101–108 (2022).
Fielding-Miller, R. et al. Safer at school early alert: an observational study of wastewater and surface monitoring to detect COVID-19 in elementary schools. Lancet Reg. Health Am. 19, 100449 (2023).
Conway, M. J. et al. Chronic shedding of a SARS-CoV-2 Alpha variant in wastewater. BMC Genomics 25, 59 (2024).
Yousif, M. et al. SARS-CoV-2 genomic surveillance in wastewater as a model for monitoring evolution of endemic viruses. Nat. Commun. 14, 6325 (2023).
Barnes, K. G. et al. Utilizing river and wastewater as a SARS-CoV-2 surveillance tool in settings with limited formal sewage systems. Nat. Commun. 14, 7883 (2023).
Tisza, M. et al. Wastewater sequencing reveals community and variant dynamics of the collective human virome. Nat. Commun. 14, 6878 (2023).
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Wongprommoon, A., Chomkatekaew, C. & Chewapreecha, C. Monitoring pathogens in wastewater. Nat Rev Microbiol 22, 261 (2024). https://doi.org/10.1038/s41579-024-01033-1
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DOI: https://doi.org/10.1038/s41579-024-01033-1
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