This month’s Genome Watch highlights discoveries of high variability in the genes underlying cytoplasmic incompatibility among Wolbachia strains that help identify the best strains to use for the control of vector-borne diseases such as Zika virus and malaria.
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References
LePage, D. P. et al. Prophage WO genes recapitulate and enhance Wolbachia-induced cytoplasmic incompatibility. Nature 543, 243–247 (2017).
Lindsey, A. R. I. et al. Evolutionary genetics of cytoplasmic incompatibility genes cifA and cifB in prophage WO of Wolbachia. Genome Biol. Evol. 10, 434–451 (2018).
Caragata, E. P. et al. Inhibition of Zika virus by Wolbachia in Aedes aegypti. Microb. Cell. 3, 293–295 (2016).
Gomes, F. M. et al. Effect of naturally occurring Wolbachia in Anopheles gambiae s.l. mosquitoes from Mali on Plasmodium falciparum malaria transmission. Proc. Natl Acad. Sci. USA 114, 12566–12571 (2017).
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Pance, A. Can Wolbachia save the day?. Nat Rev Microbiol 16, 396 (2018). https://doi.org/10.1038/s41579-018-0021-4
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DOI: https://doi.org/10.1038/s41579-018-0021-4
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