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Clinical translation of metal–organic frameworks

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This Comment discusses metal–organic frameworks and their progress towards translation in a health-care setting. We explore their prospects in clinical applications, why translation seems slow, and what opportunities and obstacles await as they move towards the clinic.

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Fig. 1: A rough timeline of important advancements in MOFs and their emerging applications in drug delivery and diagnosis.

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Author notes

  1. These authors contributed equally: Nisha Tyagi, Yalini H. Wijesundara.

Authors and Affiliations

  1. School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia

    Nisha Tyagi & Amirali Popat

  2. Department of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, TX, USA

    Yalini H. Wijesundara & Jeremiah J. Gassensmith

  3. Department of Biomedical Engineering, University of Texas at Dallas, Richardson, TX, USA

    Jeremiah J. Gassensmith

  4. Department of Functional Materials and Catalysis, Faculty of Chemistry, University of Vienna, Vienna, Austria

    Amirali Popat

Authors
  1. Nisha Tyagi
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  2. Yalini H. Wijesundara
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  3. Jeremiah J. Gassensmith
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  4. Amirali Popat
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Corresponding authors

Correspondence to Jeremiah J. Gassensmith or Amirali Popat.

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The authors declare no competing interests.

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Tyagi, N., Wijesundara, Y.H., Gassensmith, J.J. et al. Clinical translation of metal–organic frameworks. Nat Rev Mater 8, 701–703 (2023). https://doi.org/10.1038/s41578-023-00608-3

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