Quorum sensing is the regulation of gene expression programmes in response to changes in population density. It is probably best recognized as a mechanism through which bacterial communities can synchronize behaviours, such as biofilm formation and bioluminescence. This Comment article highlights the emerging evidence suggesting that quorum sensing also contributes to the regulation of immune cell responses.
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Acknowledgements
This work was supported by National Institutes of Health grants R01GM066189 (G.H.) and R01DK113790 (G.H.); the Intramural Research Program of the National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism (P.P.).
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Antonioli, L., Blandizzi, C., Pacher, P. et al. Quorum sensing in the immune system. Nat Rev Immunol 18, 537–538 (2018). https://doi.org/10.1038/s41577-018-0040-4
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DOI: https://doi.org/10.1038/s41577-018-0040-4
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