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Needle beats pill in gestational diabetes mellitus

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Given the steady increase in the use of oral antidiabetic medication, better knowledge of their effects on neonatal outcomes in gestational diabetes mellitus is essential. Recently, Marie-Victoire Sénat and colleagues investigated the use of glyburide over standard insulin treatment in a noninferiority multicentre randomized trial, which found higher risk of perinatal complications under glyburide therapy.

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Fig. 1: Lifelong impact and interactions of biological and environmental factors in the development and outcome of GDM or T2DM.

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Correspondence to Alexandra Kautzky-Willer.

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Kautzky-Willer, A., Harreiter, J. Needle beats pill in gestational diabetes mellitus. Nat Rev Endocrinol 14, 448–449 (2018). https://doi.org/10.1038/s41574-018-0050-0

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