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Strategies for the delivery of sex-based equity in cardiovascular clinical trials

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The under-representation of women in cardiovascular clinical trials persists across participant, clinician and research roles. This gap perpetuates health inequity and hampers the generation, translation and implementation of optimal evidence-based care. Urgent action is needed to address barriers, promote diversity, and ensure inclusive trial design and health-care delivery and dissemination, for more equitable cardiovascular health.

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Authors and Affiliations

  1. St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK

    Julie Sanders

  2. William Harvey Research Institute, Queen Mary University of London, London, UK

    Julie Sanders

  3. Clinical Trials Unit, Faculty of Epidemiology and Public Health, London School of Hygiene and Tropical Medicine, London, UK

    Tim Clayton, Lynn Laidlaw & Richard Evans

  4. National Heart Foundation of Australia, Melbourne, Victoria, Australia

    Stacey Matthews

  5. National Patient & Public Involvement (PPI), Leicester, UK

    Sarah Murray

  6. British Heart Foundation Clinical Research Collaborative, London, UK

    Sarah Murray

  7. National Institute of Cardiovascular Research (NICOR) Community Representation Group, London, UK

    Sarah Murray

  8. School of Nursing & Midwifery, Centre for Quality and Patient Safety Research, Institute for Health Transformation, Deakin University, Geelong, Victoria, Australia

    Rochelle Wynne

Authors
  1. Julie Sanders
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  2. Tim Clayton
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  3. Stacey Matthews
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  4. Sarah Murray
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  5. Lynn Laidlaw
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  6. Richard Evans
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  7. Rochelle Wynne
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Corresponding author

Correspondence to Julie Sanders.

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The authors declare no competing interests.

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Sanders, J., Clayton, T., Matthews, S. et al. Strategies for the delivery of sex-based equity in cardiovascular clinical trials. Nat Rev Cardiol (2024). https://doi.org/10.1038/s41569-024-01025-x

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  • DOI: https://doi.org/10.1038/s41569-024-01025-x

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