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Interventional thrombus modification in STEMI

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In ST-segment elevation myocardial infarction, the role of interventional modification of thrombi in the coronary arteries before stenting is controversial. However, innovations in stroke intervention have sparked renewed interest in thrombus modification approaches. We discuss current and emerging techniques to extract or disperse thrombi, aiming to reduce downstream embolization, microvascular obstruction and myocardial injury.

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Fig. 1: Thrombus assessment and modification verses stenting alone in STEMI.

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Author notes

  1. These authors contributed equally: Jason L. Walsh, Rafail A. Kotronias.

Authors and Affiliations

  1. Oxford Heart Centre, Oxford University Hospitals NHS Trust, Oxford, UK

    Jason L. Walsh, Rafail A. Kotronias, Adrian P. Banning & Giovanni Luigi De Maria

  2. Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK

    Jason L. Walsh, Rafail A. Kotronias, Adrian P. Banning & Giovanni Luigi De Maria

  3. National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, UK

    Adrian P. Banning

Authors
  1. Jason L. Walsh
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  2. Rafail A. Kotronias
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  3. Adrian P. Banning
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  4. Giovanni Luigi De Maria
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Corresponding author

Correspondence to Giovanni Luigi De Maria.

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Competing interests

All authors have received grant or research support (to their institution) from Medtronic and Terumo. In addition, G.L.D.M. has received grant or research support (to his institution) from Opsens and is a consultant for Corflow.

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Walsh, J.L., Kotronias, R.A., Banning, A.P. et al. Interventional thrombus modification in STEMI. Nat Rev Cardiol (2024). https://doi.org/10.1038/s41569-024-01020-2

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  • DOI: https://doi.org/10.1038/s41569-024-01020-2

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