References
Original articles
Chow, C. K. et al. Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial. Lancet https://doi.org/10.1016/S0140-6736(21)01922-X (2021)
Joseph, P. et al. Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis. Lancet https://doi.org/10.1016/S0140-6736(21)01827-4 (2021)
Related article
Chow, C. K. et al. Polypills for primary prevention of cardiovascular disease. Nat. Rev. Cardiol. 16, 602–611 (2019)
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lim, G.B. Fixed-dose combination therapy and polypills to prevent and treat CVD. Nat Rev Cardiol 18, 738–739 (2021). https://doi.org/10.1038/s41569-021-00614-4
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41569-021-00614-4
- Springer Nature Limited