A method for overcoming antibiotic resistance uses multimodal nanoparticles that target bacterial defence mechanisms while enhancing the innate immune response.
References
Zhu, J. et al. Nat. Nanotechnol. https://doi.org/10.1038/s41565-024-01648-8 (2024).
Murray, C. J. L. et al. Lancet 399, 629–655 (2022).
Otto, M. Expert Opin. Biol. Ther. 10, 1049–1059 (2010).
Liu, G. Y. et al. J. Exp. Med. 202, 209–215 (2005).
Elmesseri, R. A., Saleh, S. E., Elsherif, H. M., Yahia, I. S. & Aboshanab, K. M. Antibiotics 11, 298 (2022).
Löffler, B. et al. PLoS Pathog. 6, e1000715 (2010).
Melican, K. et al. Cell Microbiol. 10, 1987–1998 (2008).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Lang, J.C., Melican, K. Nanoparticles subdue antibiotic-resistant bacteria’s defences while enhancing innate immunity. Nat. Nanotechnol. (2024). https://doi.org/10.1038/s41565-024-01644-y
Published:
DOI: https://doi.org/10.1038/s41565-024-01644-y
- Springer Nature Limited