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Mining the microbiota for antibiotics

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The antimicrobial agent epifadin, which is produced by the nasal commensal Staphylococcus epidermidis, has— despite its short half-life — broad-spectrum activity, including against Staphylococcus aureus.

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Fig. 1: Schematic of the nasal epithelium layer colonized by bacterial commensals.

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Authors and Affiliations

  1. Helmholtz Institute for Pharmaceutical Research Saarland HIPS, Helmholtz Centre for Infection Research, Saarbrücken, Germany

    Christine Beemelmanns, Andreas Keller & Rolf Müller

  2. PharmaScienceHub, Saarbrücken, Germany

    Christine Beemelmanns, Andreas Keller & Rolf Müller

  3. Medical Faculty, Saarland University, Homburg, Germany

    Christine Beemelmanns & Andreas Keller

  4. Department of Pharmacy, Saarland University, Saarbrücken, Germany

    Rolf Müller

Authors
  1. Christine Beemelmanns
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  2. Andreas Keller
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  3. Rolf Müller
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Corresponding author

Correspondence to Rolf Müller.

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Competing interests

R.M. and A.K. are co-founders of MooH GmbH, a company that develops oral metagenomic diagnostics and probiotics.

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Beemelmanns, C., Keller, A. & Müller, R. Mining the microbiota for antibiotics. Nat Microbiol 9, 13–14 (2024). https://doi.org/10.1038/s41564-023-01568-8

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