Skip to main content
SpringerLink
Log in

Microbiology techniques

Gaming bacterial metabolism

  • News & Views
  • Published:

From Nature Microbiology

View current issue Submit your manuscript

Many microorganisms remain understudied due to the challenges and complexities of culturing. An integrated lab automation and machine learning platform called BacterAI could be the future.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: Learning appropriate culture conditions as a game.

References

  1. Louca, S., Mazel, F., Doebeli, M. & Parfrey, L. W. PLOS Biol. 17, e3000106 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Sekurova, O. N., Schneider, O. & Zotchev, S. B. Microb. Biotechnol. 12, 828–844 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Wade, W. J. R. Soc. Med. 95, 81–83 (2002).

    PubMed  PubMed Central  Google Scholar 

  4. Lewis, W. H., Tahon, G., Geesink, P., Sousa, D. Z. & Ettema, T. J. G. Nat. Rev. Microbiol. 19, 225–240 (2021).

    Article  CAS  PubMed  Google Scholar 

  5. Huang, Y. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-01674-2 (2023).

    Article  PubMed  Google Scholar 

  6. Radivojević, T., Costello, Z., Workman, K. & Garcia Martin, H. Nat. Commun. 11, 4879 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  7. Silver, D. et al. Science 362, 1140–1144 (2018).

    Article  CAS  PubMed  Google Scholar 

  8. Dama, A. C. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-023-01376-0 (2023).

    Article  PubMed  Google Scholar 

  9. Murdoch, W. J., Singh, C., Kumbier, K., Abbasi-Asl, R. & Yu, B. Proc. Natl Acad. Sci. USA 116, 22071–22080 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Arnold, C. Nature 606, 612–613 (2022).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Author notes

  1. These authors contributed equally: Jacqueline A. Valeri, Aarti Krishnan.

Authors and Affiliations

  1. Infectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA

    Jacqueline A. Valeri, Aarti Krishnan & James J. Collins

  2. Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA

    Jacqueline A. Valeri, Aarti Krishnan & James J. Collins

  3. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA

    Jacqueline A. Valeri, Aarti Krishnan & James J. Collins

  4. Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA

    Jacqueline A. Valeri & James J. Collins

Authors
  1. Jacqueline A. Valeri
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Aarti Krishnan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. James J. Collins
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to James J. Collins.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Valeri, J.A., Krishnan, A. & Collins, J.J. Gaming bacterial metabolism. Nat Microbiol 8, 1004–1005 (2023). https://doi.org/10.1038/s41564-023-01390-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41564-023-01390-2

  • Springer Nature Limited

Search

Navigation